CSF Dynamics: Modeling & Clinical Measurements

Video Poster

2019 CSF Hydrodynamics Symposium

OSLO, NORWAY - JULY 1-2, 2019

Measurements of CSF dynamics typically involve invasive lumbar puncture techniques and infusion investigations. Because of this, there is very little research done to understand how intracranial pressure (ICP) and CSF outflow resistance (measured as "Rout"s) in individuals who do not have high ICP or disordered CSF flow. Since we do not have information on how CSF normally behaves, doctors do not currently understand what qualifies as "disordered" CSF flow and, therefore, have a difficult time identifying which patients come into the clinic who will do best following shunt surgery.

Dr. Anders Eklund discusses his work at Umeå University in Sweden "lumping" different models together to try and understand these poorly described issues such as ICP, Rout and brain compliance. Dr. Eklund describes a particular study investigating the hydrodynamics associated with idiopathic normal pressure hydrocephalus patients, compared to unaffected elderly persons. Dr. Eklund concludes his presentation describing how this proposed "lumped" model can integrate what we are beginning to learn about the glymphatic system. (2019)

This presentation was made possible thanks to a generous grant from The Monkton Institute and was presented at the 2019 CSF Hydrodynamics Symposium held in Oslo, Norway.

Revised: 9/2019