Exploring the Trans-mantle Pressure Gradient in Hydrocephalus

Video Poster

2019 CSF Hydrodynamics Symposium

OSLO, NORWAY - JULY 1-2, 2019

Cooperating with another researcher met at previous CSF Hydrodynamics conferences, Dr. Harold L. Rekate discusses his and Dr. Vartan Kurtcuoglu's recent work thinking about an emerging and highly controversial issue in hydrocephalus research: the "trans-mantle pressure gradient", or TPG. The TPG is the measure of the pressure differential between the cerebral ventricles and the cortical subarachnoid space (CSAS).

While more common types of hydrocephalus are well-studied and fairly well-understood, there are variants of hydrocephalus that continue to prove difficult in treating real patients. These include infantile hydrocephalus, normal pressure hydrocephalus, normal volume hydrocephalus and negative pressure hydrocephalus. Because these types of hydrocephalus are extremely difficult to "see" with the available and current medical technologies, they can be extremely hard to diagnose and therefore, little is known about best treatment options. Dr. Rekate describes his recent work looking a potential ways to measure the TPG which, until now, has only been successfully recorded in a handful studies.

This presentation was made possible thanks to a generous grant from The Monkton Institute and was presented at the 2019 CSF Hydrodynamics Symposium held in Oslo, Norway.


Revised: 9/2019