International CSF Hydrodynamics Symposium

2015: 3rd Hydrodynamics Symposium

The 3rd symposium was held in Amiens, France, right in the historic city center, within the campus of The Université de Picardie Jules Vernes. Thank you to the conference Chairs: Diane de Zélicourt and Olivier Balédent This symposium was sponsored by The Monkton Institute, Candida Lancaster, and the Chiari & Syringomyelia Foundation.

The cerebrospinal fluid (CSF) has multiple roles in both normal brain function and neurological and neuro-developmental disorders. The barriers and interfaces of the tissues and different fluid compartments (CSF, blood and interstitial fluid) of the central nervous system (CNS) have a key role to play in the maintenance of CNS homeostasis, including fluid secretion and absorption, specialized directional transport, mechanical and chemical buffering. Given the complexity of the system at stake, the objective of the symposium was to offer a platform for the exchange of ideas and establishment of collaborations towards the modeling of the CSF and cerebrospinal fluid dynamics.

Dr. de Zélicourt is currently a senior researcher and lecturer within the Interface group at the University of Zürich (Switzerland). Her research thrust lies at the convergence of engineering and medicine, with a focus on multi-scale numerical modeling of the CSF and brain mechanics to understand the pathophysiology of hydrocephalus.

Dr. Balédent’s interest lies in Biophysics and the development and application of MRI for the non-invasive characterization of CSF hydrodynamics. He is an assistant professor at Amiens’ University Hospital (France), and head of the medical image processing department and BioFlowImage ( research team.

I would like to send my thanks for your help in organizing and funding the CSF symposium in Amiens. The talks were inspiring and the meeting format allowed for plenty of time for conversation and networking. For me at least two ideas for collaboration have emerged and will be explored when possible. Again, my thanks for helping to create this opportunity for us.

Kind regards,
Dr. Piotr Orlowski
Career Development Fellow in Imaging
Keble College, University of Oxford

Symposium Lecture Videos

*Note: You will be redirected to an external website to watch these videos.

Clinical implications of the new understanding of CSF physiology – Dr. Thomas Brinker

On the complexity of CSF flow in the upper spinal cord: is the assumption of laminar flow appropriate? – Dr. Kent-Andre Mardal

Quantitative Assessment of the differences in the resistance of spinal CSF motion in Chiari malformation – Dr. Francis Loth

Origin and clinical relevance of the cranio-spinal CSF pulsations – Dr. Noam Alperin

A multi-scale poroelastic framework for large deformations of the brain – Dr. Diane de Zèlicourt

Impact of respiration on CSF dynamics: a real time MRI investigation – Dr. Olivier Balédent

Translational biomechanics in neurodegenerative diseases – Dr. Eric Schmidt

Effects of adding poroelasticity to an existing FSI model of spinal CSF dynamics in syringomyelia – Dr. Chris Bertram

Contribution of astrocyte networks to cerebral water flow – Dr. Vartan Kurtcuoglu

Solvent flow and solute transport in perivascular channels in the brain – Dr. Michael Keith Sharp

Hardware-in-the-Loop Testing of Hydrocephalus Shunts – Dr. Marianne Schmid-Daners


Revised: 9/2019